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Aspirin poisoning antidote
Aspirin poisoning antidote











aspirin poisoning antidote

Clinical or laboratory features of toxicity.The principles of assessment of a potential salicylate overdose include: Late - Respiratory acidosis and high anion gap metabolic acidosis.

aspirin poisoning antidote

  • Early - Respiratory alkalosis and metabolic acidosis.
  • Life threatening effects following significant salicylate overdose are:
  • If there is suspicion of deliberate self-poisoning patients are to be referred for evaluation in hospital, regardless of the dose ingestedĬommon early effects following acute salicylate ingestion include:.
  • If large numbers of tablets are ingested, a large concretion (bezoar) may form in the gut, delaying absorption.
  • Early effects will be present before 6 hours.
  • Patients who ingest a large dose of salicylate may not manifest significant signs of toxicity before 6-12 hours, with subsequent rapid clinical deterioration.
  • A 10kg child can develop life threatening poisoning with the ingestion of a small sip of preparations of methyl salicylate.
  • Most acute accidental paediatric exposures of aspirin do not result in life threatening toxicity.
  • Life-threatening consequences of salicylate overdose include:.
  • Chronic toxicity has been reported from frequent application of teething gels.
  • aspirin poisoning antidote

    Accidental overdose from aspirin is very uncommon in the paediatric population, but methyl salicylate overdose is associated with significant toxicity even with very small ingestions.Infant teething gels (including bongela, sedagel).For specific details please contact Poisons Information: 13 11 26 or refer to the Toxicology and Toxinology – Therapeutic Guidelines. This guideline is a general approach to salicylate poisoning. To guide PCH ED staff with the assessment and management of salicylate poisoning in children. Clinicians should also consider the local skill level available and their local area policies before following any guideline. These clinical guidelines should never be relied on as a substitute for proper assessment with respect to the particular circumstances of each case and the needs of each patient. Clinical common-sense should be applied at all times. They are not strict protocols, and they do not replace the judgement of a senior clinician.

    aspirin poisoning antidote

    These guidelines have been produced to guide clinical decision making for the medical, nursing and allied health staff of Perth Children’s Hospital.













    Aspirin poisoning antidote